Highly diastereoselective synthesis of β-lactams by addition of titanium enolates of 2-pyridyl thioesters to chiral imines

DOI: 10.1016/S0040-4039(00)91874-4

Source and publish data:

Tetrahedron Letters p. 1113 - 1116 (1992)

Update date:2022-07-29

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Authors:

Annunziata

Cinquini

Cozzi Cozzi

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Article abstract of DOI:10.1016/S0040-4039(00)91874-4

Addition of titanium enolates of 2-pyridyl thioesters to chiral imines derived from alkoxy aldehydes occurs with good diastereofacial control, and opens a simple access to important carbapenem antibiotics.

Full text of DOI:10.1016/S0040-4039(00)91874-4

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