N-substituted pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides. A new class of diuretics

DOI: 10.1021/jm00100a001

Source and publish data:

Journal of Medicinal Chemistry p. 3977 - 3983 (1992)

Update date:2022-08-04

Topics:

Authors:

Goya Goya

Paez Paez

Alkorta Alkorta

Carrasco

Grau Grau

Anton Anton

Julia Julia

Martinez-Ripoll

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Article abstract of DOI:10.1021/jm00100a001

The synthesis and evaluation of a new class of diuretic agents derived from the pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide ring system are described. Preliminary structure-activity relationships indicate that the nature and location of the substituents

Full text of DOI:10.1021/jm00100a001

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Product name:4-amino-1-ethyl-6-phenyl-pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-dioxide

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