STEREOCONTROLLED ADDITION OF ORGANOZINC REAGENTS DERIVED FROM 2-(BROMOMETHYLACRYLATES TO CHIRAL IMINES

DOI: 10.1016/S0957-4166(00)80272-4

Source and publish data:

Tetrahedron Asymmetry p. 351 - 354 (1992)

Update date:2022-07-30

Topics:

Authors:

Dembele, Yenimegue A.

Belaud, Chantal

Hitchcock, Peter

Villieras, Jean

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Article abstract of DOI:10.1016/S0957-4166(00)80272-4

Stereocontrolled addition of isolated organozinc reagents derived from 2-(bromomethyl)acrylates to imines can be achieved with ee ca. 100percent using α-amino esters as chiral auxiliaries.High yields of pure RR or SS N-substituted α-methylene γ-lactams ca

Full text of DOI:10.1016/S0957-4166(00)80272-4

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