Synthesis of 2-deoxy-2-fluorinated inositol-1-O-dodecylphosphonates as inhibitors of glycosyl phosphatidylinositol phospholipase C

Article abstract of DOI:10.1016/0040-4039(95)01579-5

Three 2-deoxy-2-fluorinated inositols and their 1-O-dodecylphosphonate derivatives have been synthesized as non-cleavable inhibitors of glycosyl phosphatidylinositol phospholipase C. Their structure-activity relationship is discussed.