An Investigation of the Inherent Chiral Induction Ability of Axially Chiral 1,1'-Binaphthalene Framework in the Prelog's Atrolactic Acid Synthesis

Article abstract of DOI:10.1246/cl.1992.807

In the Prelog's atrolactic acid synthesis using 2'-substituted 1,1'-binaphthalen-2-ols as the chiral auxiliaries, the sense of the diastereoselection could not solely be determined by the helicity of the 1,1'-binaphthalene framework.A revised steric model