Stereoselective addition of 2-aminothiophenol to α-alkoxycinnamic acid derivatives - Alternative synthesis of (±)-diltiazem

DOI: 10.1016/S0040-4020(01)88031-5

Source and publish data:

Tetrahedron p. 8119 - 8128 (1993)

Update date:2022-07-30

Topics:

Authors:

Miyata, Okiko

Shinada, Tetsuro

Naito, Takeaki

Ninomiya, Ichiya

Date, Tadamasa

Okamura, Kimio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)88031-5

A stereocontrolled synthesis of (±)-diltiazem by applying nucleophilic addition of 2-aminothiophenol to α-alkoxycinnamic acid derivatives is described.

Full text of DOI:10.1016/S0040-4020(01)88031-5

Products guided by the article

Product name:Benzenepropanoic acid, b-hydroxy-a-[(2-methoxyethoxy)methoxy]-, ethyl ester

Cas No:142141-96-6

R&D Labs maybe for 142141-96-6

Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Sinonine Industry Co.,Ltd

Contact:86+21-56421993

Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Chinapeptides Co,. Ltd

Contact:+86-021-50792271

Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou

Relevant to this article

Trifluoroethoxy-Coated Subphthalocyanine affects Trifluoromethylation of Alkenes and Alkynes even under Low-Energy Red-Light Irradiation

Doi:10.1002/open.201600172
(2017)
Stereoselective synthesis of cis- and trans-2′,5′-disubstituted N-arylpyrrolo[3′,4′:1,9](C₆₀-I _h )[5,6]fullerenes by the 1,3-dipolar cycloaddition of azomethine ylides from dialkyl aziridinedicarboxylates to fullerene C₆₀

Doi:10.1007/s11172-012-0121-7
(2012)
Water promoted one pot three-component synthesis of tetrazoles

Doi:10.1039/c2nj40733g
(2013)
Chemical Synthesis and Enzymatic Testing of CMP-Sialic Acid Derivatives

Doi:10.1002/cbic.201200471
(2012)
Synthesis, characterization, antimicrobial activity of novel n-substituted β-hydroxy amines and βhydroxy ethers contained chiral benzoxazine fluoroquinolones

Doi:10.2174/157018013804142492
(2013)
The cyclopropyliminium rearrangement of cyclopropylthiazoles

Doi:10.1016/j.mencom.2013.01.007
(2013)

Article Doi