Stereoselective addition of 2-aminothiophenol to α-alkoxycinnamic acid derivatives - Alternative synthesis of (±)-diltiazem

DOI: 10.1016/S0040-4020(01)88031-5

Source and publish data:

Tetrahedron p. 8119 - 8128 (1993)

Update date:2022-07-30

Topics:

Authors:

Miyata, Okiko

Shinada, Tetsuro

Naito, Takeaki

Ninomiya, Ichiya

Date, Tadamasa

Okamura, Kimio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)88031-5

A stereocontrolled synthesis of (±)-diltiazem by applying nucleophilic addition of 2-aminothiophenol to α-alkoxycinnamic acid derivatives is described.

Full text of DOI:10.1016/S0040-4020(01)88031-5

Products guided by the article

Product name:Benzenepropanoic acid, b-hydroxy-a-[(2-methoxyethoxy)methoxy]-, ethyl ester

Cas No:142141-96-6

R&D Labs maybe for 142141-96-6

Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
SEA BRGIHT INDUSTRY CO.,LIMITED

Contact:0086 755 8622 3990

Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
Tianjin Anda North Industrial & Business Co.Ltd.

Contact:86-22-24999306

Address:No.11 Erwei Road,Dongli Development Area,Tianjin,China
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province

Relevant to this article

Trifluoroethoxy-Coated Subphthalocyanine affects Trifluoromethylation of Alkenes and Alkynes even under Low-Energy Red-Light Irradiation

Doi:10.1002/open.201600172
(2017)
Stereoselective synthesis of cis- and trans-2′,5′-disubstituted N-arylpyrrolo[3′,4′:1,9](C₆₀-I _h )[5,6]fullerenes by the 1,3-dipolar cycloaddition of azomethine ylides from dialkyl aziridinedicarboxylates to fullerene C₆₀

Doi:10.1007/s11172-012-0121-7
(2012)
Water promoted one pot three-component synthesis of tetrazoles

Doi:10.1039/c2nj40733g
(2013)
Chemical Synthesis and Enzymatic Testing of CMP-Sialic Acid Derivatives

Doi:10.1002/cbic.201200471
(2012)
Synthesis, characterization, antimicrobial activity of novel n-substituted β-hydroxy amines and βhydroxy ethers contained chiral benzoxazine fluoroquinolones

Doi:10.2174/157018013804142492
(2013)
The cyclopropyliminium rearrangement of cyclopropylthiazoles

Doi:10.1016/j.mencom.2013.01.007
(2013)

Article Doi