SYNTHESIS OF NOVEL DNA PHOTOCLEAVING AGENTS WITH POTENT DNA CLEAVING ACTIVITY

DOI: 10.1016/S0040-4039(00)79060-5

Source and publish data:

Tetrahedron Letters p. 2697 - 2700 (1992)

Update date:2022-08-03

Topics:

Authors:

Shinomiya, Miho

Kuroda, Reiko

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Article abstract of DOI:10.1016/S0040-4039(00)79060-5

Novel DNA photocleavers consisting of the photoactive p-nitrobenzoyl group, an intercalator an a DNA groove binder were designed and synthesized.The importance of the groove binding region to the DNA breakage ability was studied.Key Words: intercalation;

Full text of DOI:10.1016/S0040-4039(00)79060-5

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