Synthesis of 1H-1,5-benzodiazepin-2(3H)-ones from 5(4H)-isoxazolone, a heterocyclic bifunctional C-3 synthon

DOI: 10.1055/s-1992-26130

Source and publish data:

Synthesis p. 446 - 448 (1992)

Update date:2022-09-26

Topics:

Authors:

Rao Rao

Reddy Reddy

Veeranagaiah

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Article abstract of DOI:10.1055/s-1992-26130

Unsubstituted and 7- or 8-substituted 4-aryl-1H-1,5-benzodiazepin-2(3H)-ones 3a-t have been synthesized by the condensation of 3-aryl-5(4H)-isoxazolones 1a-e and parent 4-substituted 1,2-benzenediamines 2a-d under acidic conditions.

Full text of DOI:10.1055/s-1992-26130

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