Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide y (NPY)

DOI: 10.1021/jm300484d

Source and publish data:

Journal of Medicinal Chemistry p. 1811 - 1829 (2013)

Update date:2022-07-30

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Authors:

Avraham, Yosefa

Katzhendler, Jehoshua

Vorobeiv, Lia

Merchavia, Shira

Listman, Chana

Kunkes, Eithan

Harfoush, Fida'

Salameh, Sawsan

Ezra, Aviva F.

Grigoriadis, Nikolaos C.

Berry, Elliot M.

Najajreh, Yousef

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Article abstract of DOI:10.1021/jm300484d

Newly synthesized acylethanolamide derivatives oleoyl-l-valinolamide (1), oleoyl-d-valinolamide (2), elaidoyl-l-valinolamide (3), elaidoyl-d-valinolamide (4) stearoyl-l-valinolamide (5), and palmitoyl-l-valinolamide (6) were investigated in mice as antiob

Full text of DOI:10.1021/jm300484d

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