Synthesis of 6-C-substituted purine nucleosides: α-(aminomethylene)-9-β-D-ribofuranosylpurine-6-acetic acid derivatives

DOI: 10.1248/cpb.40.843

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 843 - 845 (1992)

Update date:2022-07-29

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Authors:

Hamamichi

Miyasaka

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Article abstract of DOI:10.1248/cpb.40.843

α-(Aminomethylene)-β-D-ribofuranosylpurine-6-acetamide (4) and the ethyl acetate (9) have been synthesized by catalytic hydrogenation of 6-cyanomethylenepurine derivatives (3 and 7). 6-Cyanomethylenepurines were obtained by substitution of 6-chloro-9-(2,3

Full text of DOI:10.1248/cpb.40.843

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