Journal of Medicinal Chemistry p. 3192 - 3196 (1992)
Update date:2022-07-30
Topics:
Freeman, G. A.
Rideout, J. L.
Miller, W. H.
Reardon, J. E.
3'-Azido-3'-deoxythymidine-5'-phosphonate was synthesized by five-step reaction sequence.The 5'-phosphonate was inactive against HIV-1 in MT4 cells.The absence of activity against HIV-1- was at least partially explained by demonstrating that the Km
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