Synthesis of 24-homo-26,26,26,27,27,27-hexafluoro-1α,22,25-trihydroxyvitamin D3

DOI: 10.1248/cpb.40.1346

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1346 - 1348 (1992)

Update date:2022-08-05

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Authors:

Iseki Iseki

Nagai Nagai

Kobayashi

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Article abstract of DOI:10.1248/cpb.40.1346

The novel fluorinated vitamin D₃ analog, 24-homo-26,26,26,27,27,27-1α,22,25-trihydroxyvitamin D₃, was prepared utilizing the ene reaction of hexafluoroacetone for the construction of the side chain.

Full text of DOI:10.1248/cpb.40.1346

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