Journal of Medicinal Chemistry p. 3595 - 3606 (1992)
Update date:2022-09-26
Topics: Bioavailability Statistical Analysis Experimental Design Synthetic Placebo Double-blind study Tocotrienols Hypocholesterolemic Randomized Controlled Trial LDL cholesterol
Pearce, Bradley C.
Parker, Rex A.
Deason, Michael E.
Qureshi, Asaf A.
Wright, J. J. Kim
Tocotrienols are farnesylated benzopyran natural products that exhibit hypocholesterolemic activity in vitro and in vivo.The mechanism of their hypolipidemic action involves posttranscriptional suppression of HMG-CoA reductase by a process distinct from o
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(1992)