Reduction and N-alkylation of α-methylene-indolines with sodium cyanoborohydride in carboxylic acids

DOI: 10.1080/00397919408012649

Source and publish data:

Synthetic Communications p. 701 - 707 (1994)

Update date:2022-08-04

Topics:

Authors:

Balogh Balogh

Zsadon Zsadon

Csampai Csampai

Pal Pal

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Article abstract of DOI:10.1080/00397919408012649

The reaction of α-methylene-indolines with NaCNBH₃ in carboxylic acids at room temperature can yield either 2β,3β-dihydro-indolines or their N- alkyl derivatives as main products with high selectively, depending mainly on the carboxylic acid and on the reaction time when using a large excess of NaCNBH₃.

Full text of DOI:10.1080/00397919408012649

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