Synthesis of azanorbornyl-spirodioxolanes related to the muscarinic agonist AF30

DOI: 10.1016/S0040-4039(00)74693-4

Source and publish data:

Tetrahedron Letters p. 4217 - 4220 (1992)

Update date:2022-08-04

Topics:

Authors:

MacLeod, Angus M.

Baker, Raymond

Herbert, Richard

Lewis, Richard T.

Medarde, Manuel

Street, Leslie J.

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Article abstract of DOI:10.1016/S0040-4039(00)74693-4

1-Azabicyclo[2.2.1.]heptane spirodioxolanes have been prepared with a difference in the ease of intramolecular SN₂ displacement giving an apparent epimer selectivity in the formation of fluorinated derivatives.

Full text of DOI:10.1016/S0040-4039(00)74693-4

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