Palladium-catalyzed iminocarbonylative cross-coupling reaction between haloarenes, t-BuNC, and 9-alkyl-9-BBN derivatives. Synthesis of alkyl aryl ketones

Article abstract of DOI:10.1016/S0040-4039(00)60111-9

The cross-coupling reaction between 9-alkyl-9-BBN derivatives, t-butylisocyanide, and haloarenes was carried out in dioxane at 50°C in the presence of K₃PO₄ and a catalytic amount of Pd(PPh₃)₄. The reaction provides alkyl aryl ketones in high yields after hydrolysis of the ketimine intermediates.