Synthesis of (S,S)-Isodityrosinol in a Fully Differentiated Form via Diels-Alder Methodology

Article abstract of DOI:10.1021/jo00048a005

A Diels-Alder cycloaddition reaction of an aryloxy diene 7 and an acetylenic ketone 8 derived, respectively, from L-tyrosine and D-serine leads to the synthesis of the diaryl ether unit common to isodityrosine, which upon elaboration provides the function