Tetrahedron Letters p. 317 - 320 (1989)
Update date:2022-07-30
Topics:
Bringmann, Gerhard
Geisler, Joerg-Peter
An efficient method for the asymmetric synthesis of chiral, oxygenated 1-phenylethylamines (1) in essentially two steps is described.The substituted acetophenones 2 are reductively aminated with unsubstituted chiral 1-phenylethylamine ("PEA",3), via the c
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