3'-C-branched 2'-deoxy-5-methyluridines: Synthesis, enzyme inhibition, and antiviral properties

Article abstract of DOI:10.1021/jm00102a009

A synthesis scheme for 3'-C-methyl-2'-deoxynucleosides and 3'-C- methylidene-2',3'-dideoxy-5-methyluridine has been proposed with 2- deoxyribose as the starting material. Methyl 5-O-benzoyl-2-deoxyribofuranose was oxidized and the mixture of the 3'-keto d