Ketene-S,S-Acetals As 1,3-Dipolarophiles Towards Azides. A New Synthetic Entry Into Cyclic Amino Acids

Article abstract of DOI:10.1016/S0040-4020(01)90368-0

Intramolecular azide cycloaddition reactions of ketene-S,S-acetals proceed to give a reactive imine as the initially-formed intermediate and this mechanism is supported by thermolysis of (18) which gave the stable imine (22).N-Acylation of this intermedia