Positron-emitting N-[18F]fluoroalkyl and [18]fluoropyrrolidinyl analogues of eticlopride as potential in vivo radioligands for dopamine D2 receptors

DOI: 10.1248/cpb.40.1793

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1793 - 1798 (1992)

Update date:2022-08-02

Topics:

Authors:

Maeda Maeda

Sasaki Sasaki

Fukumura

Fukuzawa

Watanabe

Kojima Kojima

Tahara Tahara

Masuda Masuda

Ichiya Ichiya

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Article abstract of DOI:10.1248/cpb.40.1793

N-Fluoroalkyl and 4-fluoropyrrolidinyl eticlopride analogues with high affinity toward central nervous system dopamine D2 receptors in vitro were labelled with positron emitting fluorine-18 (t( 1/2 ) = 110 min), and their in vivo biodistribution was inves

Full text of DOI:10.1248/cpb.40.1793

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