Chiral ligands containing heteroatoms; 9. General procedures for the synthesis of optically active 1-(2-pyridyl)alkylamines from α-amino acids

Article abstract of DOI:10.1055/s-1992-26282

General syntheses of 1-(2-pyridyl)alkylamines and N-methyl or N,N-dimethyl-1-(2-pyridyl)alkylamines from optically active α-amino acids are described. The presented procedures are based on catalyzed co-cyclotrimerization of the suitable nitriles with acet