Asymmetric synthesis of novel axially chiral 2,2′-bipyridine n,n′-dioxides bearing α-amino acid residues and their applications in enantioselective allylation of aromatic aldehydes with allyltrichlorosilane

Article abstract of DOI:10.1002/cjoc.201300090

A series of novel axially chiral 2,2′-bipyridine N,N′-dioxides bearing C₁ or C₂-symmetry have been synthesized by the use of enantiopure α-amino acids as chiral sources. The absolute stereochemistry of the axial chirality of these or