Tetrahedron Letters p. 4837 - 4840 (2013)
Update date:2022-07-30
Topics:
Ghosh, Munmun
Ahmed, Atiur
Dhara, Shubhendu
Ray, Jayanta K.
A convenient methodology has been developed towards the synthesis of substituted phenanthridines and analogous benzo[k] and benzo[i] derivatives via aerobic ligand-free domino Suzuki coupling-Michael addition reaction in the presence of Pd(OAc)2 and K3PO4 as a catalytic system in H2O at 90 C in good yields. Reaction was believed to be catalyzed by in situ generated palladium nanoparticles in water with the elimination of acetone.
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