IODINE-INDUCED CYCLISATIONS OF (E)- AND (Z)-3-HYDROXY-5-ALKENOATES: STEREOSELECTIVE APPROACHES TO TRISUBSTITUTED TETRAHYDROFURANS

DOI: 10.1016/S0040-4039(00)79028-9

Source and publish data:

Tetrahedron Letters p. 6507 - 6510 (1992)

Update date:2022-07-29

Topics: Stereoselective Tetrahydrofurans Iodine trisubstituted Cyclisations

Authors:

Bennett, Frank

Bedford, Simon B.

Bell, Kathryn E.

Fenton, Garry

Knight, David W.

Shaw, Duncan

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Article abstract of DOI:10.1016/S0040-4039(00)79028-9

Iodoetherification of the (Z)-3-hydroxy-5-alkenoates 4 leads exclusively to the hydroxy-tetrahydrofurans 5 whereas similar cyclisations of the corresponding (E)-isomers <10, 13 and 15> give largely the iodo-tetrahydrofurans <11,14 and 16>.

Full text of DOI:10.1016/S0040-4039(00)79028-9

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