Tetrahedron Letters p. 6507 - 6510 (1992)
Update date:2022-07-29
Topics: Stereoselective Tetrahydrofurans Iodine trisubstituted Cyclisations
Bennett, Frank
Bedford, Simon B.
Bell, Kathryn E.
Fenton, Garry
Knight, David W.
Shaw, Duncan
Iodoetherification of the (Z)-3-hydroxy-5-alkenoates 4 leads exclusively to the hydroxy-tetrahydrofurans 5 whereas similar cyclisations of the corresponding (E)-isomers <10, 13 and 15> give largely the iodo-tetrahydrofurans <11,14 and 16>.
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