Synthesis and stereochemistry of potential opioid-like 2,4-m-diarylsubstituted 3,7-diazabicyclo[3.3.1]nonan-9-one-1,5-diesters

DOI: 10.1002/ardp.19923251008

Source and publish data:

Archiv der Pharmazie p. 657 - 663 (1992)

Update date:2022-08-04

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Authors:

Holzgrabe

Erciyas Erciyas

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Article abstract of DOI:10.1002/ardp.19923251008

The 2,4-di-2-pyridyl-substituted 7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-one-1,5-diester shows a reasonable κ-agonistic activity in the mouse vas deferens test. - To enhance the analgetic activity derivatives with m-Cl-, m-CH₃-, m-OCH_{3
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Full text of DOI:10.1002/ardp.19923251008

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Product name:(1S,2R,4S,5R)-2,4-Bis-(3-methoxy-phenyl)-3,7-dimethyl-9-oxo-3,7-diaza-bicyclo[3.3.1]nonane-1,5-dicarboxylic acid dimethyl ester

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