Simple method for α-alkylation of α,β-unsaturated enones through the Michael addition

DOI: 10.1016/S0040-4039(00)79017-4

Source and publish data:

Tetrahedron Letters p. 6469 - 6472 (1992)

Update date:2022-07-30

Topics: Monitor the reaction Stir and Heat (if necessary) Add the Base Purify the product Characterize the product

Authors:

Hwu, Jih Ru

Hakimelahi, Gholam H.

Chou, Ching-Tai

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Article abstract of DOI:10.1016/S0040-4039(00)79017-4

Treatment of enones and Michael acceptors with a catalytic amount of 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,3-dimethyl-2-imidazolidinone at 185 °C afforded the corresponding α-substituted enones in good yields.

Full text of DOI:10.1016/S0040-4039(00)79017-4

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