
Journal of Medicinal Chemistry p. 1805 - 1809 (1994)
Update date:2022-08-05
Topics:
Arai
Kanda
Ashizawa
Morimoto
Gomi
Kono
Kasai
A series of 6-alkyl-6-demethylmitomycins (1-5) was synthesized and evaluated for anticellular and antitumor activities. These novel compounds were prepared by Michael addition of various carbanion species to 6-demethyl- 7,7-(ethylenedioxy)-6,7-dihydro-6-m
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