Synthesis of a 6H-pyrazolo[4,5,1-de]acridin-6-one derivative: A useful intermediate of antitumour agents

DOI: 10.1055/s-1994-25408

Source and publish data:

Synthesis p. 73 - 76 (1994)

Update date:2022-08-03

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Authors:

Sugaya Sugaya

Mimura Mimura

Kato Kato

Ikuta Ikuta

Mimura Mimura

Kasai Kasai

Tomioka Tomioka

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Article abstract of DOI:10.1055/s-1994-25408

A 6H-pyrazolo[4,5,1-de]acridin-6-one derivative, a useful intermediate of antitumor agents, was prepared by a facile synthetic route from 2-bromobenzoic acid and 6-nitroindazole involving a halogenocopper(I)-catalyzed Ullmann coupling reaction and Friedel-Crafts cyclization.

Full text of DOI:10.1055/s-1994-25408

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Product name:Benzoic acid, 2-[(2,2-dimethyl-1-oxopropyl)(ethoxycarbonyl)amino]-6-[(tetrahydro-2H- pyran-2-yl)oxy]-, ethyl ester

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