Synthesis of saframycins. VIII Synthesis of the ABC ring of safracins

DOI: 10.1248/cpb.40.2620

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2620 - 2626 (1992)

Update date:2022-07-29

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Authors:

Saito Saito

Obara Obara

Azumaya Azumaya

Kubo Kubo

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Article abstract of DOI:10.1248/cpb.40.2620

An efficient synthesis of the 1,5-imino-3-benzazocine derivative (18) from 1,4-diacetyl-2,5-piperazinedione (7) and 4-methoxy-3-methylbenzaldehyde (8) is described. The tricyclic lactam (18) is shown to be a useful intermediate for preparation of a phenol

Full text of DOI:10.1248/cpb.40.2620

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