Synthesis and application of imidazole derivatives. Introduction of carbogenic substituents into the 5-position of 1-methyl-1H-imidazole

DOI: 10.1248/cpb.40.2681

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2681 - 2685 (1992)

Update date:2022-08-02

Topics:

Authors:

Ohta Ohta

Yamamoto

Kawasaki

Yamashita

Katsuma Katsuma

Nasako Nasako

Kobayashi

Ogawa Ogawa

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Article abstract of DOI:10.1248/cpb.40.2681

The 5-position of 1-methyl-2-phenylthio-1H-imidazole (12a) was lithiated by lithium 2,2,6,6-tetramethylpiperidide, and the produced carbanion was reacted with various electrophiles to give the corresponding 5-substituted derivatives in good yields. The re

Full text of DOI:10.1248/cpb.40.2681

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Product name:5-(2,2-dimethyl-1-hydroxypropyl)-1-methyl-2-phenylthio-1H-imidazole

Cas No:146744-45-8

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