Cyclic and Acyclic Products from the Addition of 1-Aza-Allyl Anions to Dienes and α,β-Unsaturated Ketones - Regioselectivity

Article abstract of DOI:10.1016/S0040-4039(00)60574-9

Addition of 1-aza-allyl-lithium compound 1 to isoprene at low temperature yields two regioisomeric γ,δ-unsaturated imines 3, whereas at THF reflux temperature the cyclic regioisomeric cyclohexene derivatives 4 are formed.With 2,3-dimethylbutadiene, the ac