New Tetracyclic Derivatives of Imidazobenzodiazepines and of Imidazothienodiazepines

Article abstract of DOI:10.3987/COM-94-S(B)61

The synthesis of new tetracyclic 1,4-diazepine derivatives is described.In these compounds, an additional five-membered heterocycle is fused on the known tricyclic ring systems imidazo<1,5-a><1,4>benzodiazepine and imidazo<1,5-a>thieno<3,2-f>diazepine.Many of these new compounds display a very high affinity to the benzodiazepine receptor in mammals.