Tetrahedron Letters p. 3041 - 3044 (1985)
Update date:2022-08-05
Topics:
Cossio, Fernando P.
Ganboa, Inaki
Palomo, Claudio
Triphenylphosphine dibromide and dimethylsulfide dibromide are efficient reagents for the direct synthesis of beta-lactams from carboxylic acids and imines avoiding the use of acid halides as starting materials.Synthesis of 4-imino-beta-lactams are also briefly described.A potential synthesis of N-unsubstituted beta-lactams is made.
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