Tetrahedron Letters p. 1605 - 1608 (1993)
Update date:2022-08-02
Topics:
Ple
Turck
Martin
Barbey
Queguiner
A new synthesis of trimethoprim is described, metalation of a pyrimidine has been used in the key step. An exceptional regioselectivity in the metalation of pyrimidine derivatives has been highlighted.
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(1993)
