
Helvetica Chimica Acta p. 957 - 962 (1993)
Update date:2022-08-04
Topics:
Oppolzer, Wolfgang
Merifield, Eric
Enantiomerically pure (-)-pinidine (1) has been synthesized in 18.5 percent overall yield by a nine-step sequence starting from keto-ester 2.The key step 5 -> 6 involves an asymmetric, electrophilic enolate hydroxyamination.Diastereoselective hydrogenatio
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Doi:10.1016/j.tetlet.2019.07.001
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(1993)