Synthetic Communications p. 2859 - 2865 (2018)
Update date:2022-08-04
Topics:
Cheng, Feng
Cai, Chen
Yang, Xing
Lin, Zi-Wei
Hu, Xiao-Song
Huang, Yi-Yong
In this report, we presented a new approach to access a (1,3-butadiene-2-yl)carbinol, (1R,2R)- and (1S,2S)-1-(hydroxymethyl)-1-vinyl-1,2,3,4-tetrahydronaphthalene-2-ols. Starting from commercially available 1,4-diol-2-butyne, a six-step synthesis involving dibromination, Zn-mediated addition reaction of phenylpropyl aldehyde, epoxidation, epoxy–arene cyclization, and resolution with D(+)-Camphor afforded the title compounds.
View MoreHANGZHOU TOYOND BIOTECH CO., LTD
Contact:+86-571-86965177
Address:No. 189, Fengqi East Road, Hangzhou, China
Taizhou Shengxing Chempharm Co.,Ltd
Contact:+86-576-88516600
Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Contact:+86-574- 87178138; 87297407
Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China
Tianjin Tensing Fine Chemical Research Develop Centre
Contact:86-022-23718576,13032267585
Address:2-2-201,13 Guiyuan road,Huayuan Industry district,Tianjin,china
Chengdu Aslee Biopharmaceuticals, Inc
Contact:18608018419
Address:Chengdu Aslee Biopharmaceuticals, Inc
Doi:10.1021/jo005682n
(2001)Doi:10.1002/anie.201403666
(2014)Doi:10.1002/anie.201711286
(2018)Doi:10.1021/ja01236a015
(1944)Doi:10.1016/S0040-4020(01)81332-6
(1994)Doi:10.1021/jo00066a020
(1993)