Tryptophan-containing 1,5-tetrazole dipeptide analogs: Synthesis of Trpψ [CN4]Nle as a cis amide bond surrogate

DOI: 10.1016/S0040-4039(00)60771-2

Source and publish data:

Tetrahedron Letters p. 1757 - 1760 (1993)

Update date:2022-08-02

Topics:

Authors:

Boteju, Lakmal W.

Hruby, Victor J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60771-2

The 1,5-disubstituted tetrazole dipeptide analog Z-Trp(NⁱⁿZ)ψ[CN₄]Nle-OBzl was synthesized in good yield and high optical purity using a modified procedure of Zabrocki et al. This dipeptide analog can be selectively deprotected at either the N or the C terminal for further incorporation into peptides.

Full text of DOI:10.1016/S0040-4039(00)60771-2

Products guided by the article

Product name:3-[(S)-2-Benzyloxycarbonylamino-2-((S)-1-benzyloxycarbonyl-pentylcarbamoyl)-ethyl]-indole-1-carboxylic acid benzyl ester

Cas No:148796-08-1

R&D Labs maybe for 148796-08-1

GN chemicals co.,ltd

Contact:86 311 85902108 / 85902109

Address:room 1001-1005 ,huanghe Road ,shijiazhuang ,China
Esuccess Material Limited

Contact:852-29282288

Address:HONGKONG
Phantom-pharma

Contact:

Address:
Shreeji pharma international

Contact:0091-265-2313036

Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA
Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-88211911

Address:Keji Road NO.70

Relevant to this article

SYNTHESIS AND BIOLOGICAL EFFECTS OF ACYCLIC ANALOGS OF DEAZAPURINE NUCLEOSIDES

Doi:10.1135/cccc19930629
(1993)
A New Stereoselective Route to Branched-Chain Nitro and Amino Sugars: Synthesis of Both Enantiomers of Decilonitrose and Avidinosamine

Doi:10.1021/jo00066a029
(1993)
Synthesis, characterization, and antibacterial activities of some novel N,N'-disubstituted thiourea, 2-Amino thiazole, and imidazole-2-thione derivatives

Doi:10.1007/s00044-013-0883-y
(2014)
Scaffold Hopping-Driven Optimization of 4-(Quinazolin-4-yl)-3,4-dihydroquinoxalin-2(1 H)-ones as Novel Tubulin Inhibitors

Doi:10.1021/acsmedchemlett.9b00352
(2020)
Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs

Doi:10.1021/jm00025a010
(1995)
Photochemical properties of copper(II)-amino acid complexes

Doi:10.1021/ic50225a025
(1981)

Article Doi