New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: Synthesis and antinociceptive evaluation

Article abstract of DOI:10.1016/j.ejmech.2013.08.041

A series of substituted 6-nitrophenylpropanamide derivatives (1-20) were synthesized using either the TDAE strategy or classical organic reactions. All these compounds were characterized by fusion point, ¹H NMR, ¹³C NMR, elemental an