Tetrahedron Letters p. 819 - 822 (1993)
Update date:2022-07-29
Topics:
Wess, G.
Kramer, W.
Schubert, G.
Enhsen, A.
Baringhaus, K.-H.
et al.
Cholic acid (1) has been coupled via ω-aminoalkoxy spacer at C-3 to chlorambucil (3), HR 780 (4) and oxaproline peptide (5).Drug conjugates 9, 11, 18 exhibit strong affinity to specific bile acid transport systems.
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