New 5-HT3 (serotonin-3) receptor antagonists. V. Synthesis and structure-activity relationships of pyrrolo[2,1-c][1,4]benzoxazine-6-carboxamides.

DOI: 10.1248/cpb.43.1358

Source and publish data:

Chemical and pharmaceutical bulletin p. 1358 - 1363 (1995)

Update date:2022-08-02

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Authors:

Kato Kato

Nishino Nishino

Ito Ito

Yamakuni

Takasugi

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Article abstract of DOI:10.1248/cpb.43.1358

This paper describes the discovery of structurally novel heterocyclic carboxamides which are highly potent 5-HT3 (serotonin-3) receptor antagonists. Pyrrolo[2,1-c][1,4]benzoxazine-6-carboxamides (12 and 20) were found to possess potent 5-HT3 receptor anta

Full text of DOI:10.1248/cpb.43.1358

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