Journal of Medicinal Chemistry p. 3100 - 3107 (1994)
Update date:2022-09-26
Topics:
Thompson
Murthy
Zhao
Winborne
Green
Fisher
DesJarlais
Tomaszek Jr.
Meek
Gleason
Abdel-Meguid
The rational design and synthesis of a highly potent inhibitor of HIV-1 protease have been accomplished. The inhibitor, SB 206343, is based on a model derived from the structure of the MVT-101/HIV-1 protease complex and contains a 4(5)-acylimidazole ring
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Doi:10.1039/c3cy00572k
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(2012)Doi:10.1039/c3tc31893a
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(2014)Doi:10.1016/S0040-4020(01)89907-5
(1993)Doi:10.1021/ja00075a069
(1993)
