Stereoselective Synthesis of Trans Isomers of a Volatile Compound Isolated from the Elm Bark Beetle "Pteleobius vittatus" via Stereospecific Cyclodehydration Route

Article abstract of DOI:10.1246/bcsj.66.1738

The stereoselective asymmetric synthesis of two trans isomers of the title natural product, (3R,6R)- and (3S,6S)-tetrahydro-2,2,6-trimethyl-2H-pyran-3-ol, was achieved by starting with easily obtainable ethyl (S)-3-hydroxybutanoate, via the stereospecific