Journal of Organic Chemistry p. 4945 - 4951 (1993)
Update date:2022-08-03
Topics: Synthesis Organic chemistry Reaction Conditions Experimental Design Biosynthesis Heterocycle Strategy Marine alkaloid
Sisko, Joseph
Henry, James R.
Weinreb, Steven M.
An 11-step approach to tricyclic compound 42, which contains the alkaloidal nucleus of the marine natural product sarain A (1), has been developed.Pivotal steps in the construction of 42 include stereospecific intramolecular dipolar <3 + 2>-cycloaddition
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(1993)
