Synthesis and Structure-Activity Relationships of Naphthalene-Substituted Derivatives of the Allylamine Antimycotic Terbinafine

DOI: 10.1021/jm00071a011

Source and publish data:

Journal of Medicinal Chemistry p. 2810 - 2816 (1993)

Update date:2022-08-02

Topics: Synthesis Derivatives Naphthalene Structure-activity relationships Antimycotic

Authors:

Nussbaumer, Peter

Dorfstaetter, Gerhard

Leitner, Ingrid

Mraz, Karin

Vypel, Hermann

Stuetz, Anton

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00071a011

Derivatives of the allylamine antimycotic terbinafine (1) with varied substitution at the naphthalene ring system have been prepared, and their antifungal activity has been evaluated.In general, the potency is strongly dependent on the bulkiness of the su

Full text of DOI:10.1021/jm00071a011

Products guided by the article

Product name:(E)-2-fluoro-4-phenyl-2-penten-1-ol

Cas No:151222-56-9

R&D Labs maybe for 151222-56-9

Kraeber & Co GmbH

Contact:+49-4101-3053-0

Address:Waldhofstrasse 14 ,25474 Ellerbek Germany
Xi'an Herbland Tech Inc.

Contact:+86-29-88710656

Address:South Tai bai Road, High Tech Development Zone, Xi'an China
Huzhou City Linghu Xinwang Chemical Co.,Ltd.

Contact:86-572-3948695/3945236

Address:huzhou
WUXI HONOR SHINE CHEMICAL CO.,LTD

Contact:+86-510-83593312

Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
MINS GROUP CO.,LIMITED

Contact:18669908765

Address:Zibo City, Shandong Province, P.R.China

Relevant to this article

Synthesis of nitrogen-containing furanose sugar nucleotides for use as enzymatic probes

Doi:10.1021/ol4032073
(2014)
Synthesis and antifungal activities of myristic acid analogs

Doi:10.1002/ardp.19963291102
(1996)
Inhibition of peptidylglycine α-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals

Doi:10.1021/ja046204n
(2004)
One-pot oxidative hydrolysis-oxidative cleavage of 7-borylindoles enables access to: O -amidophenols and 4-acylbenzoxazoles

Doi:10.1039/c9cc09807k
(2020)
1-Lithio-2,2-diphenoxy-1-(phenylsulfonyl)cyclopropane as β-lithio acrylate and cyclopropanone acetal anion synthons

Doi:10.1016/S0040-4020(01)80161-7
(1993)
Efficient synthesis of new stable 1,4-diionic organosulfurs and corresponding mesoionic compounds from N -heterocyclic ylides

Doi:10.1080/10426507.2013.819866
(2014)

Article Doi