Synthesis and aldose reductase inhibitory activity of acetic acid derivatives of pyrrolo[1,2-c]imidazole

DOI: 10.1016/0223-5234(93)90016-8

Source and publish data:

European Journal of Medicinal Chemistry p. 481 - 498 (1993)

Update date:2022-07-31

Topics:

Authors:

Yamawaki

Matsushita

Asaka Asaka

Ohmori Ohmori

Nomura Nomura

Ogawa Ogawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(93)90016-8

Various acetic acid derivatives of pyrrolo[1,2-c]imidazole were prepared and evaluated for aldose reductase inhibitory activity. Most of the compounds inhibited aldose reductase isolated from rat lens in vitro and decreased sorbitol formation in sciatic n

Full text of DOI:10.1016/0223-5234(93)90016-8

Products guided by the article

Product name:4-(4-Trifluoromethyl-benzoyl)-1H-pyrrole-2-carboxylic acid ethyl ester

Cas No:151982-56-8

R&D Labs maybe for 151982-56-8

Shaanxi HuaTai Bio-fine chemical company Ltd

Contact:86-029-87862197

Address:No. 5, 3rd Floor, 29 Yanta North Road, Beilin Dist.
Mollt Biochem Co., Ltd(expird)

Contact:+86-21-38682181

Address:shanghai ,china
wuxi huabin bio-tech Co.,Ltd(expird)

Contact:86-0510-85133006

Address:hubin road NO157
shandong zhongke taidou chemical co.,ltd

Contact:86-531-88682301

Address:Jinan shandong Province CHina
Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china

Relevant to this article

Synthesis and testosterone 5α-reductase inhibitory activity of 11-substituted 4-aza-5α-androstane compounds

Doi:10.1016/0223-5234(96)85876-4
(1996)
α-Halogenohydrazides: Useful starting material for the synthesis of hydrazinoazapeptides and azauracils

Doi:10.1139/v99-013
(1999)
Regioselective glucuronidation of diosmetin and chrysoeriol by the interplay of glucuronidation and transport in UGT1A9-Overexpressing hela cells

Doi:10.1371/journal.pone.0166239
(2016)
Synthesis of trifluoromethyl-substituted conjugated enynes including a fluorinated siccayne

Doi:10.1016/S0022-1139(00)80057-3
(1993)
Benzoselenadiazole fluorescent probes-near-ir optical and ratiometric fluorescence sensor for fluoride ion

Doi:10.1021/ol403082p
(2014)
Synthetic Studies on Tricyclic Diterpenoids: Direct Allylic Amination Reaction of Isopimaric Acid Derivatives

Doi:10.1002/open.201500187
(2016)

Article Doi