
European Journal of Medicinal Chemistry p. 481 - 498 (1993)
Update date:2022-07-31
Topics:
Yamawaki
Matsushita
Asaka
Ohmori
Nomura
Ogawa
Various acetic acid derivatives of pyrrolo[1,2-c]imidazole were prepared and evaluated for aldose reductase inhibitory activity. Most of the compounds inhibited aldose reductase isolated from rat lens in vitro and decreased sorbitol formation in sciatic n
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