An Unusual Trimethylsilyltriflate Catalyzed Transformation of 6--4,5-Dihydro-3(2H)-pyridazinones Into 3-(1-Naphthyl)propionic Acid Esters

DOI: 10.1016/S0040-4039(00)79226-4

Source and publish data:

Tetrahedron Letters p. 3777 - 3780 (1993)

Update date:2022-08-05

Topics:

Authors:

Baraldi, Pier Giovanni

Manfredini, Stefano

Simoni, Daniele

Spalluto, Giampiero

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Article abstract of DOI:10.1016/S0040-4039(00)79226-4

Treatment of 6-(3-phenyl-2-hydroxypropyl)-4,5-dihydro-3(2H)-pyridazinones 6a-c with trimethylsilyl triflate (TMST) in refluxing dichloromethane gave the unexpected 3-(1-naphthyl)propionic acid ethyl ester derivatives 9a-c.The isolation of the spirotetrahy

Full text of DOI:10.1016/S0040-4039(00)79226-4

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