Synthesis of chiral NADH model compounds in the pyrrolo[3,2-b]pyridine series: Models with a chiral group on the pyrrole nitrogen or on the carboxamide side chain

Article abstract of DOI:10.1016/S0040-4020(01)87950-3

The synthesis of chiral NADH model compounds in the pyrrolo[3,2-b]pyridine series is described, using various strategies. The first route involved alkylation of the pyrrole nitrogen of a nitropyrrole carboxylate followed by a ring closure reaction in a [3