Stereoselective Total Synthesis of Polyether Ionophore Antibiotics, Isolasalocid A and Lasalocid A. Part 2. The Total Synthesis via Stereoselective Construction of the B Rings by Chelation-Controlled Cyclization under Thermodynamic Conditions

DOI: 10.1016/S0040-4020(01)87185-4

Source and publish data:

Tetrahedron p. 5997 - 6018 (1993)

Update date:2022-08-03

Topics:

Authors:

Horita, Kiyoshi

Noda, Ichio

Tanaka, Kazuhiro

Oikawa, Yuji

Yonemitsu, Osamu

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Article abstract of DOI:10.1016/S0040-4020(01)87185-4

Stereoselective total synthesis of isolasalocid A (1) and lasalocid A (2) was achieved via construction of the tetrahydrofuran rings by chelation-controlled cyclization of the corresponding p-methoxyphenyl substituted allyl alcohols (6, 7) under thermodyn

Full text of DOI:10.1016/S0040-4020(01)87185-4

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