Stereospecific Pictet-Spengler reaction: Synthesis of cis (+)-(1S, 12bR)-1-aminoindoloquinolizidine from a pure α-(S)-aminoaldehyde derivative

DOI: 10.1016/S0040-4020(01)96265-9

Source and publish data:

Tetrahedron p. 8589 - 8596 (1993)

Update date:2022-07-31

Topics:

Authors:

Melnyk, Patricia

Ducrot, Pierre

Thal, Claude

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Article abstract of DOI:10.1016/S0040-4020(01)96265-9

Pictet-Spengler reaction provides cis (+)-1-(S)-aminoindolo[2,3-a]quinolizidine in an enantio- and diastereoselective manner, using an α-aminoaldehyde derived from L-glutamic acid.

Full text of DOI:10.1016/S0040-4020(01)96265-9

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